Figure contributed by David Yule

Reviews

• Ca2+ Signaling in Pancreatic Acinar Cells - David Yule, University of Rochester
• Regulation of Physiologic and Pathologic Exocytosis in Pancreatic Acinar Cells Subhanka Dolai, Tao Liang, Laura Cose-Binker, Patrick PL Lam and Herbery Y Gaisano
• Channels and Transporters in Zymogen Granule Membranes and their Role in Granule Function: Recent Progress and a Critical Assessment - Frank Thevenod, University of Witten/Herdecke, Germany
• The Secretory Portal - Porosome in Pancreatic Acinar Cells - Bhanu Jena, Wayne State University
• Role of the Actin Cytoskeleton in Acinar Cell Protein Secretion - Robert C. De Lisle, University of Kansas

Components

• Actin
• Amylase
• Bombesin
• Caerulein
• Cholecystokinin (CCK)
• CCK receptors
• D52
• Complexin 2
• Galpha s
• Muscarinic receptors
• PLC
• Galpha q/11
• IP₃
• Inositol 1,4,5-trisphosphate receptors (InsP3R)
• NAADP
• cAMP
• cADP ribose
• Pancreatic Ribonuclease
• Ryanodine Receptor
• Secretin
• Secretin receptor
• Syntaxin
• SNAP 23
• Rab3
• Rab27
• VAMP
• Vasoactive Intestinal Polypeptide or VIP
• VIP Receptors

Methods

• Measurement of intracellular calcium concentration in pancreatic acini Matthew J. Betzenhauser, Jong Hak Wan, Hyungseo Park and David Yule
• Measuring Ca2+ dynamics in pancreatic acini using confocal microscopy Arbahim I. Orabi, Michael H. Nathanson and Sohail Z. Husain
• Permeabilized acinar cells as a tool to study the effects of membrane impermeant agents on acinar exocytosis Diana DH Thomas and Guy E Groblewski
• Visualization of exocytosis in pancreatic acinar cells by fluorescence microscopy Yujin Jang and Peter Thorn
• Purification of pancreatic zymogen granules using percoll gradients Xuequn Chen and John A. Williams
• Immunofluorescent Surface Labeling of Externalized Pancreatic Zymogen Granules or Endolysosomal Vesicles Following Exocytosis Diana D.H Thomas and Guy E. Groblewski, University of Wisconsin