Prepared by X. Chen from data in Molecular & Cellular Proteomics 7:2323, 2008.

Reviews

• Protein Composition and Biogenesis of the Pancreatic Zymogen Granules - Xuequn Chen
• Channels and Transporters in Zymogen Granule Membranes and their Role in Granule Function: A Critical Assessment - Frank Thevenod
• The secretory portal - porosome in pancreatic acinar cells - Bhanu Jena

Components

Membrane

• APP
• CaCCs
• Cysteine String Protein
• Chymase/RMCP-1
• Complexin 2
• Dynactin
• Gamma Glutamyl Transpeptidase
• GP-2
• GP-3
• ITMAP-1
• KCNQ1
• MyosinVc
• Pantophysin
• PpiB/cyclophillinB
• Presenilin
• Rab3D
• Rab6
• Rab8
• Rab11
• Rab27
• Rap1
• SCAMPs
• SNAP29
• Slp1
• Syncollin
• Syntaxin 3
• Syntaxin 7
• TWIK-2
• VAMP2
• VAMP8

Contents

• Amylase
• Carboxypeptidase
• Cholesterol Esterase (Nonspecific Lipase)
• chymotrypsinogen
• Colipase
• Deoxyribonuclease
• Elastase
• PhospholipaseA2
• PLRP1
• PLRP2
• PSTI
• Pancreatic Ribonuclease
• Triglyceride Lipase
• Trypsinogen
• ZG16

Methods

• Purification of pancreatic zymogen granules using percoll gradients Xuequn Chen and John Williams
• Channels and Transporters in Zymogen Granule Membranes and their Role in Granule Function: Recent Progress and a Critical Assessment
• Visualization of exocytosis in pancreatic acinar cells by fluorescence microscopy Yujin Jang and Peter Thorn

Data Sets

• Zymogen Granule Membrane Topology Xuequn Chen, John A. Williams and Philip Andrews