Figure contributed by Maria Eugenia Sabbatini

Reviews

• Cyclic Nucleotides as Mediators Of Acinar and Ductal Function - Thomas Albers and Maria Eugenia Sabbatini

Components

• Secretin
• Secretin receptor
• Vasoactive Intestinal Polypeptide or VIP
• VIP Receptors
• Cholecystokinin (CCK)
• Cholecystokinin Type 1 Receptor  (CCK-A Receptor)
• Somatostatin
• Somatostatin receptors
• RGS proteins
• Galpha s
• Galpha i
• Transmembrane adenylyl cyclase
• Soluble adenylyl cyclase
• Cyclic nucleotide phosphodiesterase (PDE)
• PKA
• AKAP
• PKI
• EPAC
• Rap1
• Rap1GAP
• Creb
• CFTR
• InsP3 receptors

Methods

• Microperfusion and micropuncture analysis of ductal secretion 
• Measurement of cAMP and adenylate cyclase
• Monitoring of intracellular pH and H+ fluxes in duct cells