Insulin and IGF signaling

Pathway Type: 

Signaling
AttachmentSize
Image icon ir-signaling-acini_panc.gif77.95 KB

Figure contributed by Maria Dolors Sans Gili and John A. Williams

 

Reviews

Components

  • Insulin Receptor
  • IGF receptor
  • IRS-1
  • PI3K
  • GSK3
  • Akt
  • TSC
  • TORC1
  • mTOR
  • RAPTOR
  • Rheb
  • p70s6k
  • eIF4E
  • 4E-BP1
  • shc
  • GRB2
  • SOS
  • ras
  • RAF
  • MEK 1/2
  • ERK
  • p90rsk