Pathway Type:
Signaling
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Figure contributed by Maria Eugenia Sabbatini and John Williams
Reviews
- Rho signaling in pancreatic acinar cells
Components
- Cholecystokinin (CCK)
- CCKR1
- M3 receptor
- Galpha 12/13
- P115 Rho Gef
- Larg
- PDZ-Rho GEF
- Rho GAP
- Rho GDI
- Rho A
- Rho kinase (ROCK)
- SRF
- mDia
- Actin cytoskeleton
Methods
- Quantitating the activation state in small G proteins of the Ras and Rho families by pull down assays