Diacylglycerol-PKC

Pathway Type: 

Signaling

Reviews

  • Diacylglycerol: Structure, synthesis and regulation
  • Protein kinase C

Components

  • PI-PLC
  • PLD
  • PC-PLC
  • DAG kinase
  • Gq/11
  • InsP3
  • PKC
  • RACKs
  • MARCKS proteins

Methods

  • DAG content and turnover
  • Measurement of PKC activity
  • PKC chemical inhibitors
  • Isoform specific inhibition with peptides and dominant negatives