Secretin Knockout

Model type: 

All four exons of the secretin gene were replaced with a lacZ reporter driven by the secretin promoter

Genetic background: 


Number of backcrossed generations: 



Yamagata T, Urano H, Weeber EJ, Nelson DL and Nishijima I.  Neuroscience 154:1417-1422


This line was prepared at Ohio State University by Dr Ichiko Nishijima and have been used to study brain function.  The Williams lab is using them to study pancreatic function.

They can be obtained from Dr. Williams with permission from Dr Nishijima.