Activation of stellate cells and the induction of fibrosis

Pathway Type: 

Pathophysiological

Reviews

  • Pancreatic stellate cells: Function and regulation
  • Models for the induction of chronic pancreatitis and fibrosis
  • The desmoplastic component of pancreatic carcinoma
  • Stellate cells as targets for pancreatic cancer chemotherapy

Components

  • α-SM-Myosin
  • Collagen
  • CTGF
  • Desmin
  • FGF
  • Fibronectin
  • Glial fibrillar acidic protein
  • Laminin
  • IL-1β
  • IL-6
  • MMPs
  • PDGF
  • PDGFR
  • TGFα
  • TGFβ
  • TGFβR
  • TIMPS
  • TNFα
  • Vimentin
  • Vit A

Methods