Insertion of the lacZ gene into the mouse CCK locus. The mutant is a null allele for CCK and expresses the lacZ reporter in CCK-expressing cells.
Knockout ES Line R1
Number of backcrossed generations:
Lacourse et al., Amer. J. Physiol.: GI & Liver Physiol. 39:G1302-1309 (1999) Lay et al., Dev. Dynamics. 216:190-200 (1999)
Produced by submitter who can be contacted to obtain the mice.
CCK-deficient mice are currently being established at the Jackson Laboratories for open purchase.