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PI3K–Akt–mTOR–S6K

by John A. Williams

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Pathway Type: 

Signaling
AttachmentSize
Image icon akt-mtor-pathway_panc.jpg301.55 KB

Figure contributed by Maria Dolors Sans Gili

Reviews

  • The mTOR Signaling Pathway and Regulation of Pancreatic Function - Maria Dolors Sans Gili and John A. Williams
  • The mTOR Signaling Pathway and Regulation of Pancreatic Function. (Version 2.0) - Maria Dolors Sans Gili and John A. Williams

Components

  • Cholecystokinin
  • CCKR1
  • M3 Cholinergic receptor
  • Insulin
  • Insulin Receptor
  • PI3K
  • Akt
  • AMPK
  • TSC1/2
  • Rheb
  • mTOR and the TORC1 complex
  • Raptor
  • P70S6K
  • eIF4E-BP
  • eIF4E
  • Ribosomal Protein S6
  • eEF2
  • eEF2K
  • GSK3

Methods

  • Measurement of pancreatic protein synthesis - Maria Dolors Sans Gili
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